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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RRN3
All Species:
10.11
Human Site:
S649
Identified Species:
18.54
UniProt:
Q9NYV6
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NYV6
NP_060897.3
651
74107
S649
P
V
L
Y
M
Q
P
S
P
L
_
_
_
_
_
Chimpanzee
Pan troglodytes
XP_001143837
595
67943
S593
P
V
L
Y
M
Q
P
S
P
L
_
_
_
_
_
Rhesus Macaque
Macaca mulatta
XP_001108222
651
74080
S649
P
M
L
Y
M
Q
P
S
P
L
_
_
_
_
_
Dog
Lupus familis
XP_536965
651
74211
Q642
P
A
L
Y
L
P
D
Q
S
P
L
I
T
R
V
Cat
Felis silvestris
Mouse
Mus musculus
B2RS91
656
74499
Q647
P
V
L
Y
I
P
G
Q
S
P
L
L
T
R
I
Rat
Rattus norvegicus
NP_001129318
661
75125
Q652
P
V
L
F
M
P
D
Q
S
S
L
L
S
R
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518561
660
75690
R658
P
I
M
Y
I
P
D
R
P
L
_
_
_
_
_
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001107876
612
69642
S602
R
S
P
S
S
V
G
S
P
P
A
A
F
L
R
Zebra Danio
Brachydanio rerio
XP_706962
612
68744
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_788084
611
70731
F605
S
Q
E
F
D
K
Q
F
H
F
G
S
S
P
_
Honey Bee
Apis mellifera
XP_001122533
483
56793
Nematode Worm
Caenorhab. elegans
P48322
654
75091
T651
S
A
T
P
G
L
Q
T
F
N
V
_
_
_
_
Sea Urchin
Strong. purpuratus
XP_784172
374
42533
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.4
97.6
90.6
N.A.
86.8
85.4
N.A.
76
N.A.
66.8
59.9
N.A.
29.7
27.7
24.4
28.5
Protein Similarity:
100
89
99
94.7
N.A.
92.9
91.8
N.A.
86
N.A.
79.8
76
N.A.
48.8
46.3
42.8
40.7
P-Site Identity:
100
100
90
20
N.A.
26.6
26.6
N.A.
40
N.A.
13.3
0
N.A.
0
0
0
0
P-Site Similarity:
100
100
100
33.3
N.A.
40
40
N.A.
70
N.A.
13.3
0
N.A.
21.4
0
9
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
0
0
0
0
0
0
0
0
8
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
24
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
16
0
0
0
8
8
8
0
0
8
0
0
% F
% Gly:
0
0
0
0
8
0
16
0
0
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
16
0
0
0
0
0
0
8
0
0
16
% I
% Lys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
47
0
8
8
0
0
0
31
24
16
0
8
0
% L
% Met:
0
8
8
0
31
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
54
0
8
8
0
31
24
0
39
24
0
0
0
8
0
% P
% Gln:
0
8
0
0
0
24
16
24
0
0
0
0
0
0
0
% Q
% Arg:
8
0
0
0
0
0
0
8
0
0
0
0
0
24
8
% R
% Ser:
16
8
0
8
8
0
0
31
24
8
0
8
16
0
0
% S
% Thr:
0
0
8
0
0
0
0
8
0
0
0
0
16
0
0
% T
% Val:
0
31
0
0
0
8
0
0
0
0
8
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
47
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
31
39
39
39
47
% _